None listed
Conditions
Brief summary
The willingness of the majority of Australians to adopt a sedentary lifestyle accompanied by an excess energy intake underpins the current epidemic of lifestyle diseases. In an effort to prevent the rise of inactivity-related conditions, medical and health professionals prescribe energy-restricted weight-loss programmes combined with increased physical activity as a means to reduce body mass (weight) and improve health outcomes. However, typical diet-induced weight loss leads to an imbalance in body composition that reduces an individuals’ functional capacity (i.e., movement and activity patterns) and increases their susceptibility to metabolic disorders. Specifically, the complex interactions between elevated levels of body fat and a reduced muscle size result in a high fat: muscle ratio, leading to a cascade of events that accelerate pre-existing health conditions (i.e., sarcopenia) and simultaneously predispose an individual to further (new) health risks. At present, the optimal diet to achieve weight loss and promote favourable body composition changes in overweight adults remains highly controversial. More information is needed to determine the effects of different diets on energy metabolism, energy balance and body composition. Indeed, the biggest concern for the majority of Australian adults is how to lose fat mass while preserving muscle mass and the health benefits that accrue from a nutrient-rich high-quality protein diet and physical activity. Accordingly, the aim of this project is to discover and characterise the best composition of mildly energy restricted high-protein (dairy-based), variable-carbohydrate diets consumed in association with resistance training to improve health.
Interventions
Modification of diet into two groups:
G1 = High dairy, high protein moderate carbohydrate (CHO) diet
G2 = High dairy, high protein, high CHO diet
Both groups will have their diet modified for a period of 16 weeks by a qualified dietitian. Group 1's (G1) diet will consist of foods that will make up 40% energy needs from Carbohydrates, 30% energy needs from Protein sources and 30% energy needs from Fat sources and will be individualised for each subject. Group 2's (G2) diet will consist of foods
Modification of diet into two groups: G1 = High dairy, high protein moderate carbohydrate (CHO) diet G2 = High dairy, high protein, high CHO diet Both groups will have their diet modified for a period of 16 weeks by a qualified dietitian. Group 1's (G1) diet will consist of foods that will make up 40% energy needs from Carbohydrates, 30% energy needs from Protein sources and 30% energy needs from Fat sources and will be individualised for each subject. Group 2's (G2) diet will consist of foods that will make up 55% of energy needs from Carbohydrates, 30% energy needs from Protein sources and 15% energy needs from Fat sources and will be individualised for each subject. During the 16 week dietary modification period, participants will complete 3 supervised and 3 unsupervised exercise sessions per week for the entire duration. The supervised exercise sessions will take place at RMIT University Bundoora by CERT3/4 qualified fitness instructors or equivalent. The diets will not be provided to participants but the dietitian will work with each individual to ensure they achieve the required energy ratios. There are no set number of meals, again this is based on the individual.
Sponsors
Professor John Hawley
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
35 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
Body Mass Index (BMI) between 27-40 kg/m2 i.e. classified as overweight, class I Obese or class II Obese; Sedentary
Exclusion criteria
Metabolic risk factors (hypercholesterolemia, hyperinsulinemia, and hyperglycemia, hypertenisive), heart and other organ disease, orthopaedic injury, gastrointestinal disease, clinically diagnosed dairy protein allergy, clinically diagnosed lactose intolerance.
Outcome results
None listed