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MiTii: A randomised trial of novel web-based upper limb intervention for congenital hemiplegia

A randomised control trial evaluating the functional, neurological and participation outcomes of the "Move it To improve it" program for children with congenital Hemiplegia

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611001174976
Acronym
MiTii
Enrollment
102
Registered
2011-11-10
Start date
2012-04-01
Completion date
2013-09-30
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This randomized comparison trial will test the efficacy of a novel rehabilitation (MiTii: Move it To improve it) which involves the use of a web-based, intensive and individualized, multimodal therapy program with therapists acting as 'virtual trainers', over a 20 week period, and comparing this approach to standard care received in children with congenital hemiplegia.

Interventions

MiTii (“Move it To improve it”) is an internet-based multimodal therapy which combines upper-limb training within the context of meaningful physical activity that can be accessed in children's homes. Inherent in this approach is the ability to scaffold visual perception skills and cognitive challenge, both important aspects of activity engagement and participation in a virtual training environment. The program is potentially cost effective as only three centre-based therapists (Physiotherapist,

MiTii (“Move it To improve it”) is an internet-based multimodal therapy which combines upper-limb training within the context of meaningful physical activity that can be accessed in children's homes. Inherent in this approach is the ability to scaffold visual perception skills and cognitive challenge, both important aspects of activity engagement and participation in a virtual training environment. The program is potentially cost effective as only three centre-based therapists (Physiotherapist, Occupation Therapist, and psychologist) are required to provide initial assessment, goal setting and training for families and participating children. Each therapist then spends 30 minutes each week to remotely modify the individualised program. This current application proposes to test the efficacy of MiTii in a wait list randomised controlled trial. We propose to provide MiTii at an intensity of 30 minutes per day, 6 days/week for 20 weeks (total dose 60 hours). All children will therefore receive the therapy within 10 months of being randomised either to commence MiTii immediately or waitlisted for 20 weeks before receiving the same Mitii therapy as the Immediate invention group. Retention of effects will be tested at 10 months. As current therapy programs are resource intensive and time consuming it is important to determine if gains from MiTii are sustained over a 10 month period as this could offer a cost effective model of care, particularly for rural, remote and isolated children with CP.

Sponsors

Smart Futures Coinvestment Fund
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
8 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

i. Gross Motor Function Classification (GMFCS) I or II; Manual Abilities (MACs) I, II, III. ii. Sufficient co-operation and cognitive understanding to perform the tasks and access the computer equipment; iii. Are able to attend 3 appointments in Brisbane for initial assessment/training and follow-up assessments. iv. Able to access the internet at home (phone line or internet access). Note; laptops will be loaned for those require them and camera’s provided for all children with the treatment phase.

Exclusion criteria

i. received upper limb surgery in the last 6mths; ii. unstable epilepsy (i.e. not controlled by medication) is a precaution for TMS. Where children have received BoNT-A or upper limb casting in the previous 1 month, inclusion in the study will be delayed until after treatment and standard follow up.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 23, 2026