None listed
Conditions
Brief summary
This study aims to determine the safety and efficacy of a tailored exercise program in prostate cancer patients with bone metastases. Who is it for? You may be eligible to join this study if you are a man with prostate cancer with diagnosed bone metastases. Trial details. Participants in this trial will be randomly (by chance) allocated to one of two groups. One group will undergo supervised exercise training. This involves resistance, aerobic (stationary cycling) and flexibility exercises, three times per week over a period of 3 months and then will be monitored (without training) for a further 3 months. The other group will be assigned to no treatment for the first 3 months. After this time participants in this group will commence the exercise program for the next 3 months. Participants will complete some tests of physical function and questionnaires about fatigue, pain and physical activity levels, and have their body composition measured at these time points. It is thought that the exercise program will be safe and will improve physical function when compared to no training.
Interventions
Exercise Group:
The modular multi-modal physical exercise intervention program will comprise resistance (10-12-RM), aerobic (60-85% HRmax) and flexibility exercises undertaken 3 times per week for 3 months. Participants will be reassessed again at 6 months. Exercise training sessions will take approximately 60 minutes and will be conducted in small groups of up to 6 participants under supervision of an exercise physiologist
Sponsors
Edith Cowan University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
Male
Age
0 to No maximum
Healthy volunteers
No
Inclusion criteria
Men with prostate cancer and established bone metastases.
Exclusion criteria
Men participating in regular exercise (structured aerobic or resistance training two or more times per week) within the past 3 months. Acute illness or cardiovascular/neurological disorders that could inhibit exercising. Not ambulatory without assistance. Current fracture, or fracture within the last 6-months
Outcome results
None listed