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Dairy milk's potential as a functional food for improved cellular DNA integrity study

To determine whether consumption of cow milk improves the capacity of human cells to maintain integrity of their genetic material in healthy volunteers

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611001147976
Enrollment
16
Registered
2011-11-02
Start date
2011-10-26
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

It is a three week randomised crossover study investigating if consumption of cow milk improves the capacity of human cells to maintain integrity of their genetic material. The study will involve three interventions (each drink once only) comparing the effect of 500ml reduced fat milk (2% fat) with that of 500ml orange juice and 500ml water. Participant will be fasting overnight. The next morning they will donate first blood sample. Ten minutes later they will ingest 500ml of the assigned drink,

It is a three week randomised crossover study investigating if consumption of cow milk improves the capacity of human cells to maintain integrity of their genetic material. The study will involve three interventions (each drink once only) comparing the effect of 500ml reduced fat milk (2% fat) with that of 500ml orange juice and 500ml water. Participant will be fasting overnight. The next morning they will donate first blood sample. Ten minutes later they will ingest 500ml of the assigned drink, which must be consumed within 5 minutes. More blood will be collected 1.5 hours, 3.0 hours and 4.5 hours after consumption of the drinks. There is 1-week wash-out period between each intervention.

Sponsors

The Dairy Research Institute
Lead SponsorCommercial sector/Industry

Study design

Allocation
Randomised controlled trial
Primary purpose
Prevention

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

Healthy subjects aged 20-40 years Not undergoing treatment for life-threatening diseases Not taking vitamin or micronutrient supplements at doses that exceed 25% of the recommended dietary intake. Consume less that 250ml of milk per day Consume less than 100g of semi-solid (e.g. yoghurt) or solid dairy foods (e.g. cheddar cheese) per day

Exclusion criteria

Unable to attend an information session and/or read the information sheet Females who are planning a pregnancy or are pregnant Current smokers Those who drink more than two standard drinks of alcohol per day. Body Mass Index 30 or greater Diagnosed with diabetes Lactose intolerance

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026