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The effect on birth outcomes of discussions in early pregnancy, emphasising the importance of eating fish.

The effect on birth outcomes, especially birthweight, head circumference and other indices of fetal wellbeing, of discussions with women attending a UK antenatal clinic at 20 weeks' pregnancy or less , during which the benefits of eating fish during pregnancy were emphasised.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611001123932
Enrollment
2837
Registered
2011-10-27
Start date
1998-04-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Research findings indicate that pregnant women should increase their intake of oily fish before, during and after pregnancy and that they should breastfeed. Despite this advice, no direct evidence exists that increased oily fish intake during pregnancy is beneficial to birth outcomes. In addition the possible effectiveness of personalised dietary advice given to women antenatally has been little-investigated. The nutritional advice approach differs from that of fish oil supplementation as eating fish is a dietary choice and oily fish may have effects differing from those of supplementation because of the many nutrients present in addition to omega-3 fatty acids. In an study carried out at Whipps Cross Hospital by Dr Michel Odent a single discussion session was held at or before 20 weeks gestation, at which stage of pregnancy, the brain growth spurt and rapid endothelial growth begin, that focused on an increased intake of oily fish and a reduced intake of trans-fatty acids. Trends to greater birthweight, head circumference, body length and to a lower incidence of low birthweight were observed. Thus the effect of giving advice to pregnant women to increase intake of oily fish was sufficiently positive to indicate the value of further study. Controlled prospective studies exploring the effect of encouraging consumption of oily fish and a reduction in the intake of trans-fatty acids have not been carried out. The benefits of improving maternal nutrition before and during pregnancy and throughout lactation are many. The health of the baby is dependent on maternal nutrition and there is evidence to suggest that small birth size is a major contributor to the cause of adult disease, including hypertension, coronary heart disease, type II diabetes and renal disease. Treating and caring for people with coronary heart disease costs Britain about £7billion each year, according to the British Heart Foundation, and the cost of caring for patients with type II diabetes is estimated by Diabetes UK to be £3.5billion annually. There are clear public health benefits in reducing the incidence of low birthweight and consequently the prevalence of these debilitating and costly diseases. It is hypothesised that a one-to-one informal discussion with pregnant women before 20 weeks gestation, emphasising the benefits to mother and fetus of oily fish consumption, will result in improved birth outcomes.

Interventions

One informal one-to-one discussion of 15 - 20 minutes, between the researcher and pregnant women at 20 or fewer weeks gestation, covering lifestyle and diet, in which the benefits of eating fish, especially oily fish, were emphasised. The interviewees were all attending antenatal clinic at a UK hospital for the first time in that pregnancy and had no apparent complications of this pregnancy to date. The intervention was in addition to the standard antenatal care offerd by the hospital clinic.

Sponsors

The Seafish Industry Authority
Lead SponsorCommercial sector/Industry

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Educational / counselling / training
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Women up to and including 20 weeks gestation, making their first visit to the antenatal clinic in their current pregnancy

Exclusion criteria

Patients under 18 years old unless accompained by a responsible adult who could sign consent Epileptics Women with a recent psychiatric history Patients taking part in existing studies, where inclusion may adversely affect either project Women with a poor obstetric or medical history Known drug users Non-English speaking women if a translator was not available

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026