None listed
Conditions
Brief summary
Background: The ingestion of high-fat meals impairs endothelial function in adults and this impairment is attenuated by exercise. The response of young people to these nutritional and physiological stressors has not been established. Objectives: To investigate if endothelial function is impaired following the ingestion of a high-fat breakfast and lunch in adolescent boys, and if a bout of moderate-intensity exercise could attenuate any impairment if present.
Interventions
In a randomised cross-over design, participants will either be inactive or complete sixty minutes of moderate intensity exercise (treadmill walking at 60% of peak oxygen uptake) in the late afternoon (4 - 5 pm) prior to the ingestion of a standardised high-fat breakfast and lunch.
The breakfast provides 1.5 g fat (60% Energy), 1.8 g carbohydrate (33%), 0.4 g protein (7%) and 92.9 kJ per kilogram body mass. The lunch provides 1.1 g fat (50%), 1.9 g carbohydrate (37%), 0.6 g protein (13%) and 84
In a randomised cross-over design, participants will either be inactive or complete sixty minutes of moderate intensity exercise (treadmill walking at 60% of peak oxygen uptake) in the late afternoon (4 - 5 pm) prior to the ingestion of a standardised high-fat breakfast and lunch. The breakfast provides 1.5 g fat (60% Energy), 1.8 g carbohydrate (33%), 0.4 g protein (7%) and 92.9 kJ per kilogram body mass. The lunch provides 1.1 g fat (50%), 1.9 g carbohydrate (37%), 0.6 g protein (13%) and 84.6 kJ per kilogram of body mass. Breakfast is consumed between 08:30 - 09:30 and lunch 3.5 hours later between 12:00 - 13:00. Each trial will be separated by a period of seven days.
Sponsors
Loughborough University
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
12 Years to 14 Years
Healthy volunteers
Yes
Inclusion criteria
1. Aged 12 - 14 years 2. Male
Exclusion criteria
1. Smoking 2. Known metabolic disease 3. On medication that affects lipid or carbohydrate metabolism 4. Individuals with any known bleeding disorder
Outcome results
None listed