None listed
Conditions
Brief summary
This randomised, double-blind and standardised clinical trials investigated the clinical effectiveness of pulsed Nd:YAG Laser induction of pulpal analgesia compared with 5% EMLA The current study strengthens other reports of the clinical effectiveness of Nd:YAG Laser induction of pulpal analgesia in a carefully planned and standardised, blinded controlling manner. Further studies are however needed to define the optimal Laser parameters, the reversibility of the analgesic effect and the follow-up induced changes on tooth morphology and the pulp for Laser-induced pulpal analgesia. Of particular significance is that Laser-induced pulpal analgesia is effective, minimally invasiveness and therefore, has significant implications world-wide particularly in underdeveloped countries. anaesthetic cream.
Interventions
1) A pulsed Nd:YAG Laser (The American Dental Laser, Sunrise technologies Inc., California, USA., model, dLase300)had an emission wavelength of 1064nm, at 150 microsceond pulse duration. The mean average power of 1.1+ 0.2W, 15Hz; 60-87mJ energy pulse; energy density: 73-107J/cm2; total energy: 211- 312J.
2)0.5mg of 5% EMLA cream (2.5% lignocaine and 2.5% prilocaine), was applied to the buccal mucosa via a plastic syringe and secured in place with oral bandage for 20mins.
These two interventions
1) A pulsed Nd:YAG Laser (The American Dental Laser, Sunrise technologies Inc., California, USA., model, dLase300)had an emission wavelength of 1064nm, at 150 microsceond pulse duration. The mean average power of 1.1+ 0.2W, 15Hz; 60-87mJ energy pulse; energy density: 73-107J/cm2; total energy: 211- 312J. 2)0.5mg of 5% EMLA cream (2.5% lignocaine and 2.5% prilocaine), was applied to the buccal mucosa via a plastic syringe and secured in place with oral bandage for 20mins. These two interventions happen during the same, single session. For each subject, a pair of bilateral premolar teeth was randomly allotted as i) the Laser plus Sham EMLA or ii) Sham Laser plus EMLA groups by an independent person who neither operated the Laser nor tested the analgesic effects. Analgesia was assessed by cutting a standardised-cavity and recorded by EPT and carried out by an operator not applying Laser nor assessing the VAS score. The sham EMLA participants will always receive the real-Laser. And the the real-EMLA participatants will always receive the sham-Laser Subjects wore ear headphones with no sound and Laser-protective goggles to maintain double-blindedness and for safety. Baseline EPT was measured and recorded prior to treatment. The buccal sulcus adjacent to the test tooth was dried, and 0.5mg of EMLA or Sham EMLA cream applied via a syringe, secured and isolated with an Orahesive bandage (Convatec, Victoria, Australia). 15 minutes after EMLA or Sham EMLA sulcular application, Laser or Sham Laser, was applied in a focus (1mm away) scanning-motion at 3mm/sec over cervical half of the buccal and the lingual/palatal tooth surfaces to a total of 240sec (120sec/surface) and the EPT reading recorded immediately. After five minutes, a standardised cavity was cut at the cervical half of the buccal surface with a high-speed-diamond-bur. Subjects indicated sensitivity by raising their hand and drilling and EPT recording terminated immediately and VAS (0-100mm) recorded.
Sponsors
Ambrose Chan
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
14 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
Orthodontic young patients who required a paired bilateral premolar tooth extraction from either dental arch. All teeth were vital, restoration and caries-free with good periodontal health. Subjects had good health.
Exclusion criteria
Subjects have history of allergy to local anaesthetic or have pacemakers, hearing aids and other attached electronic devices were excluded.
Outcome results
None listed