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Is ballistic strength training more effective than usual care for improving mobility following traumatic brain injury (TBI)?

Is ballistic strength training more effective than usual care for improving mobility following traumatic brain injury (TBI)?

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611001098921
Acronym
TBStrong
Enrollment
131
Registered
2011-10-21
Start date
2012-03-09
Completion date
2021-06-22
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Traumatic brain injury (TBI) is the leading cause of death and disability amongst adolescents and young adults. The incidence of TBI in Australia is 300 per 100,000, of which 20% are classified moderate to severe. The prevalence of TBI in the community is high because of the survival rate and the demographic groups at most risk are adolescents and young adults. Although a minority of people who sustain a moderate to severe TBI can expect to make a full recovery, over 75% of victims never return to full independence and function. In contrast to the vast literature on neuropsychological impairments following TBI, surprisingly little information is known about the effect of the brain injury on gait. My recent systematic review found the key biomechanical abnormalities of gait were yet to be determined. Further, the key physical impairments contributing to mobility limitations have not been established. Several studies have suggested balance may be primarily responsible. Although balance, spasticity, contracture, muscle weakness and inco-ordination may all contribute to mobility limitations, my research has identified that balance and strength deficits are most prevalent, but the primary cause of mobility limitations was muscle weakness. Physiotherapy is routinely provided to treat the physical impairments that contribute to mobility limitations in order to optimize rehabilitation outcomes for people with TBI. Balance training and muscle strengthening programs are widely used. Strong evidence exists indicating balance training improves balance disorders and strength training improves muscle weakness in neurological populations, yet little evidence exists supporting the impact of either intervention on mobility limitations. Further, a recent international symposium on research priorities for TBI highlighted the urgent need for rehabilitative therapy research as virtually no level 1 evidence exists. The primary aim of this research program is to investigate whether ballistic strength training is more effective than usual carer for improving mobility following TBI. The research program constitutes a randomised controlled trial (RCT) comparing ballistic strength training and usual care for improving mobility following TBI.

Interventions

The intervention group will perform ballistic strength training exercises in a context specific manner according to the American College of Sports Medicine (ACSM) guidelines to ensure an optimal training stimulus and transfer of training gains. Participants will perform ballistic strength training exercises tailored to the severity of their strength deficits. The major muscle groups of the lower limbs responsible for mobility will be targeted ballistically in functional positions. They include

The intervention group will perform ballistic strength training exercises in a context specific manner according to the American College of Sports Medicine (ACSM) guidelines to ensure an optimal training stimulus and transfer of training gains. Participants will perform ballistic strength training exercises tailored to the severity of their strength deficits. The major muscle groups of the lower limbs responsible for mobility will be targeted ballistically in functional positions. They include the hip flexors and extensors, knee flexors and extensors, and ankle plantarflexors. Strength training is a relatively safe intervention with very few adverse events reported for people with neurological conditions. In order to ensure the exercises are conducted in a ballistic manner, a physiotherapist will supervise each session. The supervising physiotherapists will be responsible for ensuring that exercises are completed according to four key criteria. These are 1) Type of muscle contraction (concentric/isometric/eccentric), 2) Targeted range of motion (ROM), 3) Speed and 4) Load. Participants will have 3 one-hour sessions/week for 12 weeks in a 1:1 format supervised by a physiotherapist.

Sponsors

Epworth Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

Participants must have a neurologically based movement disorder affecting mobility as a result of TBI and be less than 12 months post injury.

Exclusion criteria

- were unwilling or unable to provide informed consent - have a previously diagnosed central nervous system disorder - have severe cognitive or behavioural problems that prevent assessment - have orthopaedic injuries restricting mobility

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 13, 2026