Mifepristone for early termination of pregnancy.

Termination of early pregnancy using mifepristone 200mg followed by buccal administration of misoprostol 800mcg – retrospective review of efficacy and safety – Australian Authorised Prescriber Program.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12611001051932

Acronym

Enrollment

13000

Registered

2011-10-07

Start date

2009-08-09

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A retrospective review of the safety and efficacy of the use of mifepristone 200mg with misoprostol 800mcg buccally for termination of pregnancy less than 9 weeks gestation. Summary of the findings from an Authorised Prescriber program in Australia.

Interventions

Mifepristone 200mg tablet followed 36-48 hours later by misoprostol 800mcg tablets by buccal administration. Observation for adverse events for up to 21 days post treatment.

Eligibility

Sex/Gender

All

Age

14 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

Confirmed pregnancy up to 9 weeks gestation. Informed consent. No contraindications. Must meet legal requirements for termination of pregnancy in the state where the service is provided.

Exclusion criteria

More than 9 weeks since the last menstrual period (confirmed by ultrasound). Known or suspected ectopic pregnancy. Concomitant administration of anticoagulants or corticosteroids. Adrenal failure, inherited porphyria or a haemorrhagic disorder. Allergy to mifepristone or misoprostol. Intrauterine device insitu Pelvic infection

Outcome results