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Non melancholic depression: a naturalistic treatment outcome study

The effect of in-house psychological treatment at the Black Dog Institute Depression Clinic on severity of symptoms in participants with non-melancholic depression who have tried two or more antidepressants

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611000932965
Acronym
Non-Melancholic Depression Study
Enrollment
100
Registered
2011-08-30
Start date
2011-08-17
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The current research aims to determine whether changing the treatment paradigm from a drug to a non-drug (i.e psychological) approach will result in improved outcomes for those with a unipolar non-melancholic depression. By altering the primary treatment approach, we hypothesise that more positive outcomes are likely to occur.

Interventions

All treatment in this trial forms part of routine clinical management. Patients in the "treatment" group receive ten 50 minute sessions with a Black Dog Institute Clinical Psychologist over a 12 week period. The first 8 sessions are weekly, and the last two sessions are fortnightly.There is no uniform psychological treatment used for all patients - rather, treatment type is tailored to the patients particular concerns (as it would be in the "real" world).

Sponsors

Department of Health and Aging
Lead SponsorGovernment body

Study design

Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

Diagnosis by BDI Psychiatrist of non-melancholic depression Over 18 years old Tried two or more antidepressants - at least one must have been a trial of more than 4 weeks with cessation not entirely due to side effects Not have received psychological therapy within the last 3 months

Exclusion criteria

Under 18 years old Significant comorbidities present Current drug and alcohol problems

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026