Synbiotic supplementation: effects on faecal microbiota and immunity in physically active individuals.

Comparing Digestion 1-2-3-4 with acacia gum on gut bacteria and indices of immunity in physically active male adults

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000807954

Enrollment

Registered

2011-08-01

Start date

2008-02-16

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to compare a synbiotic supplement containing pre- and probiotics, bovine lactoferrin and bovine immunoglobulines with acacia gum on gut bacteria and indices of immunity. The study will provide consumers with evidence based advice on the use of a synbiotic supplement.

Interventions

Experimental intervention: 3 capsules daily for four weeks of Digestion 1-2-3-4, which contains per capsule 200mg glycomax immunoglobulin, 50mg of lactoferrin, 4.6x10e8 Lactobacillus paracasei, 6x10e8 Bifidobacterium Lactis, 4.6x10e8 Lactobacillus acidophilus, 4.6x10e8 Lactobacillus rhamnosus, 90mg Raftiline and 10mg Raftilose GR.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

Male

Age

18 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

Undertaking a minimum 3 exercise sessions per week, have a minimum VO2max (maximum oxygen uptake) of 45ml/kg/min and not have taken antibiotics for a period of one month before the start of supplementation.

Exclusion criteria

Individuals outside of the age or VO2max range, taking immunomodulating medications, asthmatics and individuals with irritable bowel symptoms.

Outcome results