None listed
Conditions
Brief summary
The aim of this project is to study a new way of cleaning the bowel prior to colonoscopy. Current methods of cleaning the bowel are very effective but have some limitations. Bowel preparation currently involves drinking a large volume of salty tasting fluid which many patients do not like. An alternative method involves drinking a smaller volume of solution that can cause complications associated with dehydration and decreased salt levels within the body. In this study we will evaluate a new way of cleaning the bowel involving the use of a more gentle tablet laxative and diet restrictions in the three days before your colonoscopy. We are also interested in how you as the patient feel about this method of cleaning the bowel and we will ask you to fill in a questionnaire prior to your colonoscopy. The laxative we are using in this trial (Dulcolax) is freely available and works by stimulating the colon to pass bowel motions. It is a safe drug that is proven to be effective in helping empty the bowel. Dulcolax (bisacodyl) is approved by the Therapeutic Goods Administration of Australia to treat constipation and evacuation of the bowel. This study will be conducted at The Western Hospital Footscray. 200 people will be asked to participate in this trial.
Interventions
Arm 1: Bisacodyl tablets and diet restrictions for three days prior to colonoscopy. 10mg twice daily and low residue diet to prepare the bowel for investigation.
Arm 2: Prepkit C which is the standard bowel preparation at The Western Hospital taken the day prior to the procedure. Contains 1 x GlycoPrep-C 70g sachet and 2 x Picoprep 15.5g sachets
taken with water.
Low residue diet as designed by study dietician includes:
Fruit - Apple juice allowed. Not allowed fresh and dried fruit, jam or oth
Arm 1: Bisacodyl tablets and diet restrictions for three days prior to colonoscopy. 10mg twice daily and low residue diet to prepare the bowel for investigation. Arm 2: Prepkit C which is the standard bowel preparation at The Western Hospital taken the day prior to the procedure. Contains 1 x GlycoPrep-C 70g sachet and 2 x Picoprep 15.5g sachets taken with water. Low residue diet as designed by study dietician includes: Fruit - Apple juice allowed. Not allowed fresh and dried fruit, jam or other juices. Vegetables - Mashed pumpkin and potato allowed. Not allowed other vegetables or salad of any kind, no peas, beans or lentils. Protein - Well cooked chicken, fish or poached eggs allowed. Not allowed other meats, sausages, gravy, backed beans or spagetti. Dairy - Limited to 2 serves per day with no cheese. Carbohydrates - Boiled white rice or pasta, white bread, rice bubbles allowed. Not allowed brown rice/pasta, no wholegrain bread, no nuts or seeds, no other cereals. Fluids - Water, tea, coffee, milk sport drinks allowed. Not allowed alcohol, orange juice, prune juice or tomato juice.
Sponsors
Dr Paul Simpson
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
All patients presenting for colonoscopy at The Western hospital.
Exclusion criteria
Women who are pregnant and the human foetus. Children and/or young people (ie. <18 years) People with an intellectual or mental impairment People highly dependent on medical care
Outcome results
None listed