None listed
Conditions
Brief summary
The hypothesis is that overtraining syndrome due to hypothalamic dysfunction and that Eleutherococcus will assist in preventing overtrainign syndrome. Evidence for hypothalamic dysfunction is made by changes in waking core body temperature, and also by measuring changes in corticotrophic releasong hormine (CRH) which is released by the hypothalamus in times of stress. This hormone CRH in turn stimulates the pituitary gland to release adrenocorticotrophic hormone (ACTH) which stimulates the adrenal cortex to release cortisol. Cortisol is a stress hormone. All three of these hormones are measured at 0, 6 and 12 weeks. The study will determine if there is any difference in these hormones between the control cohort and the active ingerdient cohort
Interventions
Eleutherococcus senticosus (Araliacae: Siberian ginseng). Two tablets each taken twice daily. Each tablet contains 1g of Eleutherococcus senticosus. Total daily dose of Eleuthrococcus senticosus is 4 g per day. Participants will take the tablets for the final 6 weeks of the 12 week trial. The first 6 weeks of the trial involves elucidating from the daily heart rate and core temperature measurement as well as the blood samples and time trials whether the individuals are at risk of developing
Eleutherococcus senticosus (Araliacae: Siberian ginseng). Two tablets each taken twice daily. Each tablet contains 1g of Eleutherococcus senticosus. Total daily dose of Eleuthrococcus senticosus is 4 g per day. Participants will take the tablets for the final 6 weeks of the 12 week trial. The first 6 weeks of the trial involves elucidating from the daily heart rate and core temperature measurement as well as the blood samples and time trials whether the individuals are at risk of developing overtraining syndrome or not. Participants will take the herbal remedy for a total of 6 weeks as this is the standard time that this rememdy is given. This will make it comparable to clinical situations.
Sponsors
Murdoch University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Athletes entered in an Ironman triathlon
Exclusion criteria
Medically diagnosed conditions, medically diagnosed cognitive impairment, participants currently on prescribed medication for any condition except the oral birth control pill
Outcome results
None listed