Effects of sitting up for 5 minutes vs. immediately lying down after spinal anesthesia for cesarean delivery on fluid and ephedrine requirement

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000746932

Enrollment

120

Registered

2011-07-18

Start date

2010-08-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study was to determine the effect of sitting the patient up for 5 minutes after spinal anesthesia before lying down on intraoperative fluid and ephedrine (a medication that raises blood pressure) requirement. We hypothesized that this delayed upright position will minimize the usual decrease in blood pressure after spinal anesthesia and will therefore decrease the amount of fluid and ephedrine usually required to maintain the blood pressure within normal range in these patients.

Interventions

Intervention: sitting up for 5 minutes after spinal anesthesia then lying down to a tilted supine position

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

- Females - 18-40 years of age - Pregnant at term (greater than or equal to 37 weeks gestation) - Singleton uncomplicated pregnancy - American Society of Anesthesiologists’ physical class I or II

Exclusion criteria

- hypertension - any hypertensive disease of pregnancy - diabetes mellitus - any contraindication to regional anesthesia - allergy to any of the study medications

Outcome results