Multi-centre audit of ACE inhibitor associated angioedema

A retrospective case note audit of symptoms, signs and management of patients attending hospital accident and emergency departments with angioedema who are currently taking an ACE inhibitor

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12611000708954

Acronym

MAAAA

Enrollment

Registered

2011-07-08

Start date

2011-06-10

Completion date

2012-12-12

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is an audit of patients who present to hospital with angioedema (swelling around the head and neck) associated with the use of a common blood pressure medication, the ACE inhibitors. The purpose is to try to determine how frequently this problem occurs across a range of hospitals, and also, to provide more information to enable an estimation of the proportion of cases where there is serious concern (ie threatened or real airway obstruction or death).

Interventions

All patients included in the audit will have been exposed to an ACE inhibitor medication as part of their routine treatment. There will be no additional exposures as part of the conduct of the study. The audit is of patients presenting to hospital emergency departments with angioedema between Jan 2008 and Dec 2010. The occurance of angioedema is the outcome being observed.

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

Angioedema - ICD 9 Code 995.1, or ICD 10 Code T 78.3 must be on an ACE inhibior

Exclusion criteria

not taking an ACE inhibitor

Outcome results