NSW Cancer Lifestyle and Evaluation of Risk Study (CLEAR Study)

A multi-centre case-control surveillance study in the NSW population to provide ongoing data on the relative importance of known or emerging exposures and their relationships to leading or emerging cancer types.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12611000678998

Acronym

CLEAR

Enrollment

10000

Registered

2011-07-05

Start date

2007-01-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The NSW Cancer, Lifestyle, and the Evaluation of Risk (CLEAR) Study is a multi-centre case-control surveillance study in the NSW population. The objectives of the study are: 1. To provide ongoing data on the relative importance of known or emerging exposures and their relationships to leading or emerging cancer types. 2. To investigate in the short term once sample sizes permit, the effects of migration, ethnicity, physical activity, alcohol consumption, smoking, reproductive history, occupation, screening behaviour and certain dietary patterns on the risk of developing cancer of the colon and rectum, prostate, breast and lung, cutaneous melanoma and non-Hodgkin lymphoma. 3. To investigate in the longer term, once sample sizes permit, the effects of these factors on rarer cancer types, such as hepatoma, thyroid, ovarian and pancreatic cancers. 4. To develop a recruitment infrastructure and biological repository of sufficient size to enable the testing of new hypotheses on gene and environment factors, and in some situations, gene-environment interactions, on the risk of cancers affecting the Australian population.

Interventions

Questionnaire (survey) and a blood sample (optional). Survey questions relate to lifestyle and risk factors a person may have been exposed to during their lifetime. Data from questionnaires of cancer patients and cancer free controls will be compared. Blood samples will be analysed in the future in a quest to identify known or new biomarkers for disease. Data from blood analyses fror cancer patients and cancer free controls will be compared. This is a one-off intervention: completion of one

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Aged 18 years or over; live in NSW; diagnosed with a primary cancer in the past 18 months. Partners of cancer patients(if there is one) who are cancer free (never had a cancer) are also included in the study.

Exclusion criteria

People who have had a previous cancer are not eligible for the study.

Outcome results