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Do health benefits of vegetable derived compounds on healthy blood flow depend on the structure they were consumed in?

Effect of food structure on the bioavailability and the bioactivity of vegetable derived compounds on the healthy blood flow of healthy adults -a crossover study.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611000656932
Enrollment
10
Registered
2011-06-27
Start date
2011-10-03
Completion date
2011-11-04
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Inclusion of fruit and vegetables as part of our daily diet is a general requirement to keep the body healthy. However, recent studies show that certain fruit and vegetables possess specific health compounds (independent of their antioxidant properties) that not only help maintain a healthy gut but once absorbed may (i) maintain healthy blood flow, which may reduce the susceptibility to formation of blood clots and facilitate tissue maintenance, creating an general improvement in health and well-being. As the first part of our study, we aim to establish ex vivo functional assays, which will then be applied in a large scale feeding trial to evaluate the effect of vegetable-derived compounds on platelet aggregation. to explore how the consumption of selective vegetable-structured foods may enhance cardiovascular health.

Interventions

Platelet aggregation before and after consuming vegatables in various food structures. there will be two treatments (liquid form of vegetable (approximately 250mL) and solid form (approximately 100g)of vegetable). Meal (breakfast) consumed once only over a period of approximately 20 minutes. The wash-out period will be 48 hours.

Sponsors

New Zealand Institute of Plant and Food Research
Lead SponsorGovernment body

Study design

Allocation
Non-randomised trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

Healthy adult males

Exclusion criteria

Smokers On regular medications

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026