Comparison between two clomiphene citrate protocols for induction of ovulation in clomiphene resistant Polycystic ovarian disease.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000639921

Enrollment

200

Registered

2011-06-23

Start date

2009-01-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of the study is to test if either doubling the dose of clomiphene citrate or doubling the duration would make previously unresponsive patients respond and ovulate, and to compare the efficacy of either approach.

Interventions

clomiphene citrate oral tablets 100 mg daily for 10 days, starting within 5 days of induced menses.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

20 Years to 35 Years

Healthy volunteers

Inclusion criteria

married, nulligravida, polycystic ovarian disease, resistant to clomiphene citrate drug in previous cycle/s

Exclusion criteria

previous pelvic surgery, other causes of infertility, BMI>35

Outcome results