Therapeutic effect of saffron on cognitive function in multiple sclerosis patients

Therapeutic effect of saffron compared to a placebo on cognitive function and depression in definitive multiple sclerosis patients

Status

Not yet recruiting

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000610932

Enrollment

Registered

2011-06-14

Start date

2011-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Memory dysfunction is a common undesirable symptom in Multiple sclerosis. According to the proved effect of saffron in memory deficit of Alzheimer disease, we hypothesis that it may be helpful for MS patients too.

Interventions

saffron capsule 30mg/kg/day for 16 weeks

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Healthy volunteers

Inclusion criteria

Definitive diagnosed MS with MC-donald 2010 criteria 3 of 5 memory domain involvement(BRB-N test) Do not use any treatment for memory function up to 3 month before intervention Ability to do the test and fill the questionnaire him/herself

Exclusion criteria

Other cause of cognitive impairment other than MS MS attack in previous month before intervention Severe depression according to Beck-2 in the beginning of the intervention Alcohol or drug abuse among the study Pregnancy

Outcome results