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Does scopolamine improve attention more than placebo in healthy volunteers and what does this tell us about mechanisms of attention?

Does scopolamine improve selective attention and cognition more than placebo in healthy male volunteers?

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611000603910
Enrollment
25
Registered
2011-06-10
Start date
2011-06-20
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Attentional processing is a cognitive skill that allows us to interpret and act in our environment. Although this skill is important, little is understoond about the neurochemical processes that are important to attention. This study will allow us to assess the importance of different brain chemicals in contributing to selective attention function.

Interventions

A single dose of scopolamine (0.8mg contained in one capsule) (1-2 week washout between conditions)

Sponsors

The University of Queensland
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
Male
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

Healthy volunteers Aged 18-40 years Male

Exclusion criteria

Current psychiatric or neurological diagnosis Current use of psychotropic medication Current use of cholinergic or anticholinergic medication Medical condition in which scopolamine is contraindicated

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026