Glycaemic effects of Omega-3 (GEO) - Can omega-3 (fish oil) supplementation improve insulin sensitivity in middle aged males?

Can dietary supplementation with n-3 long chain polyunsaturated fatty acids compared with placebo improve insulin sensitivity in overweight middle aged males?

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000602921

Acronym

GEO

Enrollment

Registered

2011-06-10

Start date

2012-01-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Omega-3 supplements are very commonly used by people in the community for a multitude of purposes. Recent studies have suggested a way that they could improve the way the body processes sugar and in doing so reduce the risk of developing diabetes, and maybe help to treat it. However this has not been adequately tested in humans. This study aims to test this in an at risk group, middle aged males.

Interventions

n-3 long chain polyunsaturated fatty acids from marine source at a dose of 1.4g/day for 8 weeks given in the form of oral capsules. There will be a 4 week washout period between swapping treatments.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

Male

Age

35 Years to 54 Years

Healthy volunteers

Inclusion criteria

Body Mass index 25-30 kg/m2

Exclusion criteria

Prexisting medical conditions under treatment Hypertension Allergy to fish or seafood Using prescription pharmaceuticals, neutraceuticals, antioxidants or other supplements Smoker Planning to change level of exercise or fish intake during the course of the study

Outcome results