None listed
Conditions
Brief summary
This study will randomise all patients with 5-15% mid dermal burns attending the BPTC for first review with LDI confirmation of a mid-dermal burn into two groups; Group 1 will have Biobrane and Acticoat dressings to burn wounds and group 2 will have the regularly used acticoat dressings alone, in the conventional manner. Burns will undergo standard ward hydrodebridement or OT hydrodebridement (if necessary for analgesia). Biobrane will be secured with hypafix on the ward or rarely, if necessary in OT with staples. Both groups will then be reviewed at regular dressing changes according to the usual practise at CHW for whichever Acticoat is used. Biobrane will be removed at D14 and decision on healing made then clinically and with a Vapourometer. Scar outcome and need for grafting will be assessed as well as cost effectiveness, healing time and amount of pain at dressing changes. We feel that this study may improve clinical care by providing evidence to support the use of Biobrane and the benefits to its use will in the long term outweigh the extra costs involved.
Interventions
The comparison of two dressings in current use - Group 1 -a biosynthetic silicone and nylon fabric bound with porcine collagen (Biobrane) will be dressed with biobrane and acticoat (as per the standard practise) . Dressings will be changed once per week for two weeks at which point a decision will be made regarding the need for grafting (as per the standard practise); Group 2 will have a nano-crystalline silver antimicrobial barrier dressing (Acticoat). This dressing will also be chnaged once pe
The comparison of two dressings in current use - Group 1 -a biosynthetic silicone and nylon fabric bound with porcine collagen (Biobrane) will be dressed with biobrane and acticoat (as per the standard practise) . Dressings will be changed once per week for two weeks at which point a decision will be made regarding the need for grafting (as per the standard practise); Group 2 will have a nano-crystalline silver antimicrobial barrier dressing (Acticoat). This dressing will also be chnaged once per week for two weeks at which point a decision will be made as to whether skin grafting is necessary (as per the standard practise)
Sponsors
The Children's Hospital at Westmead
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
1 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
paediatric mid dermal burns between 5 and 15% total body surface area, consent obtained
Exclusion criteria
any burns to face, digits and perineum any burn not confirmed to be mid-dermal on LDI scan on day two of presentation
Outcome results
None listed