None listed
Conditions
Brief summary
In a randomised design participants will be allocated to one of three conditions. Participants in the first condition will receive the standard CPT treatment. Those in the second condition will receive behavioural activation then CPT. And those in the third condition will receive CPT then behavioural activation. Given that research has not specifically examined the utility of using a combined treatment protocol for those with comorbid PTSD and MDD, the third condition will be added in an attempt to examine whether treatment presentation order makes a significant difference to treatment outcomes. Participants will be assessed at pre-treatment, mid-treatment, post-treatment and at a 6-month follow up. The project will use standardised self-report and structured clinical interview measures, and will use assessors blind to treatment condition at post- and follow-up assessments. It is predicted that: 1.Participants in all conditions will demonstrate a significant reduction in depression and PTSD symptoms. 2.Participants in the combined treatment conditions (behavioural activation then CPT or, CPT then behavioural activation) will show a greater reduction in PTSD and depression symptoms compared to participants in the CPT condition. 3. The relationship between depression symptoms and treatment outcomes (i.e., reduced PTSD and depression symptoms) will be mediated by emotional engagement.
Interventions
The study is comparing three different treatment conditions. Arm 1: Cognitive Processing Therapy only. CPT will follow the manual written by Resick, Monson, and Chard (2007). Therapy will be administered weekly, in a one on one setting (i.e., therapist and client). Therapy will be conducted over 12 to 15 weekly sessions. Sessions will last between 60 and 90 minutes. Sessions one and two will introduce the concepts of PTSD and CPT and will involve the client writing an impact statement. The impact statement will allow the therapist and client to identify stuck points (i.e., problem areas in thinking). During session three the client will be taught to identify and label their thoughts and feelings and the relationship amongst events, thoughts and emotions. During sessions four and five the client will generate and read their trauma account to the therapist. Through Socratic questioning the therapist will begin questioning self-blame and other distorted thoughts. The therapist will continue to work through stuck points during session six. Thus, sessions one through six will aim to teach the client to challenge their thoughts of the trauma and to identify problematic cognitions. The following sessions will teach the client cognitive therapy skills and focus on topics that have been disrupted by the trauma. During session seven clients will use worksheets to develop and practice using more balanced self-statements. Sessions eight through 12 will ask the client to focus on one theme each week (i.e., safety, trust, power, esteem, intimacy) and correct overgeneralised beliefs related to the theme. Within session 11 the client will write another impact statement and this revised statement will be used in session 12 to evaluate gains made in treatment and where the client wishes to continue working. During session 12 clients will also receive information related to relapse prevention. The core therapy protocol will consist of 12 weekly sessions. However, in order to increase the clinical validity of the protocol, up to 3 additional sessions will be offered if necessary to target any residual PTSD or depressive symptoms still present after 12 weeks of treatment. This is routine clinical practice in a community setting. Arm 2: Behavioural Activation then Cognitive Processing Therapy. Therapy will be manualised. Therapy will be administered weekly, in a one on one setting (i.e., therapist and client). The treatment will be based on the Behavioural Activation intervention for depression (Martell, Addis, & Jacobson, 2001), and CPT for PTSD (Resick, et al., 2007). Therapy will consist of 15 sessions lasting between 60 to 90 minutes each. The first five sessions will be depression focussed and utilise Behavioural Activation techniques. The first five sessions will focus on the link between behaviour and mood and involve psychoeducation, activity monitoring, and mastery and pleasure tasks (Martell et al., 2001). During session one clients will receive a treatment rationale along with information regarding PTSD and depression symptoms. During session two clients will discuss the cycle of depression and its’ relation to inactivity. Clients will be presented with a weekly activity scheduling task in which they must monitor what they do during the week and how these activities make them feel. This task aims to allow the client to become aware of their mood/anxiety levels, triggers and consequences. During session three the activity monitoring task will be reviewed and the TRAP (trigger, response, avoidance, pattern) model discussed. The therapist will then explain the importance of scheduling pleasant events and the significance of elevating activity. The client will then be assigned a pleasant event scheduling task to complete during the following week. Through the use of role plays and worksheets session four and five will then aim to teach the ACTION model and demonstrate the importance of elevating pleasant activities in everyday life. The ACTION model contains the following components: Assess how the behaviour serves you (what outcome/consequences do you expect when you decide not to go out with friends? Why do you choose to be alone? Scared to get hurt again/embarrassment, etc.) Choose to either avoid or activate (what will be the outcome of you going out with friends? Distraction from negative thoughts, social support, etc.) Try out the behaviour that has been chosen (or try out a new behaviour that you find might lead to a positive outcome) Integrate any new behaviour into a routine (make those behaviours that make you feel good part of your daily life) Observe the outcome (continue your detective work) Never give up! The remaining sessions will be trauma focussed. These sessions will incorporate exposure, and cognitive therapy with a focus on the themes of safety, trust, intimacy, power/control, and esteem (Resick, et al., 2007). Session six will provide the client with information about PTSD symptoms and CPT. During session seven clients will write an impact statement. In session eight clients will identify thoughts and feelings and the connection between thoughts and feelings. During sessions nine and ten clients will work through their trauma accounts and stuck points will be identified. Sessions 11 and 12 will ask clients to further work through stuck points and patterns of problematic thinking. Sessions 13 through 15 will then ask clients to work through themes of safety, trust, power, esteem, intimacy and correct overgeneralised beliefs related to the theme. Session 15 will also involve the provision of relapse prevention information. Arm 3: Cognitive Processing Therapy than Behavioural Activation. Therapy will be administered weekly, in a one on one setting (i.e., therapist and client). This condition will follow the same procedures as the Behavioural Activation then CPT condition but the CPT and Behavioural Activation components will be presented in the reverse order. That is, the first set of 10 sessions will be trauma focused and the next five sessions will utilise Behavioural Activation techniques.
Sponsors
Study design
Eligibility
Inclusion criteria
Participants will be recruited if they: (a) are fluent in English, (b) have been exposed directly or indirectly (witnessed) to trauma (motor vehicle accidents, industrial accidents, interpersonal assault etc) four or more weeks ago, (c) meet a full or sub-threshold diagnosis for Post Traumatic Stress Disorder and (d) if participants are on psychotropic medications, agree to maintain a stable course of medication for the duration of therapy.
Exclusion criteria
Exclusion criteria Exclusion criteria for research purposes comprise: inadequate comprehension of English. For clinical reasons, clients with the following presentations would not normally be offered short-term trauma-focussed therapy in any service: (a) moderate to severe traumatic brain injury, (b) uncontrolled psychosis, (c) current substance dependence, (d) already currently in an active, trauma-focussed therapy, (e) significant risk of harm (e.g. in current domestic violence situation) or (f) active suicidality. Withdrawal criteria As a matter of standard clinical management and ethical procedures, participants would be withdrawn if it was felt that therapy was either inappropriate or if there was a significant decline in the person’s well-being (e.g., if they required hospitalisation for self-harm concerns etc).