None listed
Conditions
Brief summary
The purpose of the study is to assess whether a high dose, stabilised green-lipped mussel extract is effective in the treatment of osteoarthritis of the knee, assessed by pain, mobility, gastrointestinal function and quality of life measures. We hypothesis that altered gut function (i.e. such as constipation, diarrhoea, reflux, bloating) may affect how successful green-lipped mussel is in improving the knee pain and mobility. Gut function may be altered due to the underlying condition of osteoarthritis, medication intake or altered gut flora.
Interventions
New Zealand Green-Lipped Mussel extract 500mg per capsule
dose: 3000mg per day (3 caps twice per day)
duration: 8 weeks
Sponsors
Good Health Australia Pty Ltd
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
- Knee osteoarthritis diagnosed by Rhuematologist - not taking any form of herbal/multivitamin/nutritional supplements (i.e. glucosamine, fish oil, green-lipped mussel) 4 weeks before recruitment - in otherwise good health -
Exclusion criteria
- concurrent use of any other investigational product - unintended weight loss of more than 15% of body weight within 6 months before recrutiment - active substance abuse (alcohol or drug dependency) - breast feeding, pregnant or planning to become pregnant - smokers - allergy/intolerances to shellfish (mollusk or crustaceans)
Outcome results
None listed