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Randomised Controlled Trial of Pre-Procedure Virtual Bronchoscopy Planning Compared To Conventional Computed Tomographic Planning For Endobronchial Ultrasound Guide Sheath Procedures

In patients with peripheral pulmonary nodules who are undergoing EBUS GS directed biopsies, does pre-procedure planning with iLogic InReach virtual bronchoscopy software improve diagnostic yield and lesion localisation whilst also reducing procedure time and complication rate when compared to pre-procedure planning with conventional bi-axial CT scans?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611000501943
Enrollment
120
Registered
2011-05-13
Start date
2011-06-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The study aims to investigate whether using iLogic inReach (superDimension) virtual bronchoscopy software to pre-plan lung biopsy procedures results in more accurate diagnosis of lung lesions as well as shorter procedure times and lower complication rates when compared to conventional planning of lung biopsy procedures using digital copies of CT scans

Interventions

The iLogic inReach (superDimension) software creates a virtual bronchoscopic map as well as a three dimensional external map of the bronchial tree from information obtained from CT scan data. It also provides simultaneous review of CT scan images in three different planes (coronal, axial, sagittal). The bronchoscopist will use this software to map a pathway to the target lesion and will then review the intended pathway by virtual bronchoscopy. This planning method will take 5-30 minutes. T

The iLogic inReach (superDimension) software creates a virtual bronchoscopic map as well as a three dimensional external map of the bronchial tree from information obtained from CT scan data. It also provides simultaneous review of CT scan images in three different planes (coronal, axial, sagittal). The bronchoscopist will use this software to map a pathway to the target lesion and will then review the intended pathway by virtual bronchoscopy. This planning method will take 5-30 minutes. The EBUS GS system consists of a radial ultrasound probe which is inserted into a flexible guide sheath in the working channel of the bronchoscope. Ultrasound images help the bronchoscopist determine the density of the tissue which the radial probe is passing through. Normal lung produces a "snow storm" appearance whereas mass lesions show a well defined border which represents the change in density between normal aerated lung and the solid mass. The radial ultrasound probe is then removed and the pre-measured biopsy forceps and cytology brushes are then pass through the guide sheath to sample the target lesion.

Sponsors

Queensland Health
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

Age 18-85 Patients with a peripheral pulmonary nodule undergoing EBUS GS directed biopsy for diagnosis

Exclusion criteria

Pregnancy Inability to provide consent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026