Using ultrasound guided access to radial and femoral arteries to reduce bleeding in patients undergoing coronary angiography or angioplasty

A comparison of transradial versus transfemoral and standard versus ultrasound-guided approaches in reducing bleeding rates in patients undergoing coronary angiography or angioplasty.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000489998

Acronym

SURF

Enrollment

1388

Registered

2011-05-10

Start date

2012-11-10

Completion date

2017-11-01

Last updated

2021-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to determine which of two different approaches in accessing an artery, transfemoral (via the artery in the groin) or transradial (via the artery in the wrist), both of these are currently used in clinical practice, is least associated with bleeding and procedural related complications. It will also determine whether using an ultrasound machine to guide the arterial access will reduce bleeding and other procedural related complications.

Interventions

Randomisation 1: Transradial approach to arterial access. Both the femoral and the radial artery are routinely used as entry sites for coronary angiography and angioplasty. Although femoral artery access is more common, radial artery access is associated with reduced bleeding complications. The procedure may take 30minutes to 1 hour. Randomisation 2: Ultrasound-guided access The operator will use an ultrasound probe to guide the needle into the femoral/radial artery. The procedure may take

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

All patients over 18 years of age who present to the cardiac catheter lab

Exclusion criteria

1. Cardiogenic shock or intubated patients 2. Previous CABG 3. Negative Allen’s test 4. Known difficulties (including previous unsuccessful access) with femoral (i.e. Leriche syndrome, severe peripheral artery disease, large abdominal aortic aneurysm) or radial access (Raynaud syndrome). 5. Simultaneous right heart catherisation 6. Pregnant 7. Haemodialysis patients with an arteriovenous fistula 8. Inability to give informed consent or unable to apply with all requirements

Outcome results