Skip to content

Randomised trial of different stitching techniques for skin surgery.

Randomised comparison trial of superficial dermal Maxon suture with Fixomull closure vs standard deep dermal two layer closure technique vs single layer interrupted nylon closure after elliptical skin excision; scar width and cosmesis at six and twelve months.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611000483954
Enrollment
186
Registered
2011-05-10
Start date
2010-04-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

There are various suturing techniques used to repair wounds after skin surgery. This study was designed to assess the differences between two of these existing techniques, as well as a 'new' technique in terms of scarring.

Interventions

1. Maxon full closure of dermis with fixomull epidermal closure. Involves closure of all dermal layers with a buried interrupted Maxon suture. Epidermal closure effected with fixomull. Sutures are absorbable and are left in place. Fixomull removed after three weeks. OR 2. Nylon interrupted closure of all layers. All skin layers closed with simple interrupted nylon sutures, removed day 7 for wounds on the face, and day 14 for wounds on other areas. After this, fixomull is applied over the wound

1. Maxon full closure of dermis with fixomull epidermal closure. Involves closure of all dermal layers with a buried interrupted Maxon suture. Epidermal closure effected with fixomull. Sutures are absorbable and are left in place. Fixomull removed after three weeks. OR 2. Nylon interrupted closure of all layers. All skin layers closed with simple interrupted nylon sutures, removed day 7 for wounds on the face, and day 14 for wounds on other areas. After this, fixomull is applied over the wound for three weeks.

Sponsors

Nicholas Bostock-Ling
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Simple elliptical skin excision Adults Enrolment from all eligible patients attending a skin cancer clinic that have elected to undergo surgical excision of a skin lesion (benign or malignant).

Exclusion criteria

Ellipse length <25mm Dermis too thin for valid comparison Allergy to materials used

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026