Combination of furosemide and albumin for treatment of edema in chronic kidney disease patients

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000480987

Enrollment

Registered

2011-05-10

Start date

2010-07-27

Completion date

2011-11-01

Last updated

2021-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Comparison the efficacy of diuretic between furosemide and furosemide plus albumin in stable CKD patients by measuring urine output and urine sodium.

Interventions

crossover study treatment with furosemide 40 mg plus albumin 10 gm intravenously one time or with furosamide 40 mg intravenously alone one time and then 2 week washout period before moving onto the alternate treatment.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

Stable CKD patients were defined as patients who have GFR < 60 mL/min per 1.73m2 and no fluctuation of GFR > 10% with in 2 months

Exclusion criteria

Patients with GFR < 10 mL/min per 1.73m2, critically ill patients such as congestive heart failure, acute renal failure, shock, on respirator and previous history of furosemide usage within two week

Outcome results