None listed
Conditions
Brief summary
Objective: To evaluate if only the type of fat ingested at breakfast as butter (saturated fat), margarine (polyunsaturated fat) and olive oil (monounsaturated fat) has power to modify the lipid profile and anthropometric variables of postmenopausal women at risk of cardiovascular disease (CVD). Subjects and methods: We conducted a randomized, crossover and longitudinal study in 60 postmenopausal women at risk of CVD who were randomly assigned to receive during a period of one month each type of breakfast: 3 study periods (breakfast with the same composition plus butter/margarine/olive oil) separated by two 45-day washout periods. In fasting conditions, on the first and last day of each study period, weight, arterial blood pressure, heart rate and adiposity were recorded and a blood sample was collected to determine plasma lipid profile (total cholesterol, LDLc, HDLc and triglycerides) and other inflammation parameters
Interventions
We conducted a randomized, crossover and longitudinal study in humans who were randomly assigned to receive during a period of one month each type of breakfast: 3 study periods (breakfast with the same composition [200 ml Semi skimmed milk+ 18 g of soluble coffee ( 1 monodose sachette)+8 g of sugar ( 1 monodose sachette)+ 2 toasts of bread white] plus 20 g of butter/margarine/olive oil in breakfast A/B/C respectively. Each study period is separated by one washout period (45-day). The compositio
We conducted a randomized, crossover and longitudinal study in humans who were randomly assigned to receive during a period of one month each type of breakfast: 3 study periods (breakfast with the same composition [200 ml Semi skimmed milk+ 18 g of soluble coffee ( 1 monodose sachette)+8 g of sugar ( 1 monodose sachette)+ 2 toasts of bread white] plus 20 g of butter/margarine/olive oil in breakfast A/B/C respectively. Each study period is separated by one washout period (45-day). The composition of breakfast in washout period is: 200 ml Semi skimmed milk+ 18 g of soluble coffee ( 1 monodose sachette)+8 g of sugar ( 1 monodose sachette)+ 2 tosts of bread white +50 g of jam of peach + 200 ml of pineapple juice. This was an interventionist, longitudinal, randomized and crossover clinical trial where the participants consume each breakfast daily for a period of one month (30 days). Each participant consume each breakfast daily for a period of one month (30 days).The nutritional composition of breakfast and the other meals of the day was identical for all the volunteers, except the type of fat contributed in the breakfast each month.
Sponsors
JUANA Ma MORILLAS RUIZ
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
- Postmenopausal women - Caucasian white women
Exclusion criteria
- volunteers gender male - women who are not postmenopausal - women with nutritional rare habits (vegetarians, persons who do not consume lacteal, diets of slimming) - Women who are disease of absorption of fats - Women with psychiatric disease
Outcome results
None listed