Effect of Propofol on Ability to Drive

Estimation of the simulated driving ability of post-surgical patients with varying Propofol plasma concentrations

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000385943

Enrollment

Registered

2011-04-13

Start date

2011-06-14

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Administration of Propofol via intravenous infusion a) The dose will be titrated to achieve an estimated plasma concentration of 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 mg/mL in stepwise progression b) the infusion will be continuous and will not exceed 30 minutes

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients undergoing day-case surgery at Monash Medical Centre; Patients that are expected to be receiving a Propofol based anaesthetic.

Exclusion criteria

Below 18 years of age; Insufficient English comprehension to understand consent form; Too ill to participate as judged by the Prinipal Investigator; Patient refusal; Known allergy to Propofol; Absent limb or limbs; Documented cerebrovascular accident; Documented intra-cranial space occupying lesion; No current driver’s licence.

Outcome results