A Randomized controlled trial comparing Topical use of Mupirocin versus Medihoney for the prevention of infection at Tenckhoff Exit Site in Peritoneal Dialysis Patients

Status

Suspended

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000297921

Acronym

TUMMIE Trial

Enrollment

380

Registered

2011-03-21

Start date

2011-04-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

not recruiting

Interventions

Once daly application of Topical Medihoney (gauze pad) approximately10 mg ( size of a pea) at Peritoneal dialysis catheter exit site once daily (the medihoney dressing will be changed daily ) compared topical application of small amount Mupirocin using cotton bud to Peritoneal dialysis catheter exit site once daily ( 12 months )

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. Patients on peritoneal dialysis.( Incident and prevalent) 2. Able to give informed consent

Exclusion criteria

1. PD patients who had exit site infection, peritonitis, or tunnel infection within the last 4 weeks 2. Known hypersensitivity to, or intolerance of, honey or mupirocin. 3. On long term antibiotics for any reason. 4. Patients with a history of psychological illness or condition which interferes with their ability to understand or comply with the requirements of the study.

Outcome results