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Reducing disability in older Australians through secondary stroke prevention.

A randomised controlled trial to investigate the effectiveness of a model of integrated, evidence based management of modifiable cardiovascular risk factors and post stroke depression, in stroke survivors returning to the care of their general practitioner.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12611000264987
Acronym
ICARUSS
Enrollment
300
Registered
2011-03-11
Start date
2008-02-26
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Stroke survivors can be faced with many problems including the physical disability resulting from the stroke, interruption and often cessation of gainful employment, disruption to family life and the onset of post stroke depression. Stroke survivors are also at a much higher risk of experiencing further stroke. Effective management of stroke risk factors including, high blood pressure, high cholesterol, smoking, excessive alcohol intake and obesity, can significantly reduce the likelihood of a recurrent stroke. However, there remains a considerable gap between published and evidence-based guidelines for stroke prevention and the reality of care received by stroke survivors. The Integrated CAre for the RedUction of Secondary Stroke Project (ICARUSS) is an integrated, multi-modal model of care for the management of risk factors in stroke survivors that was developed from a shared care model. Its goal is to reduce mortality and disability by reducing the recurrence of stroke. Initial results of a pilot study suggest that it is practical, feasible and of great importance to stroke survivors, there carers, and the community in general. The model is now being tested on a broader scale throughout Australia.

Interventions

1. Nurse coordinated evidence based quarterly follow up of participants in the community, in a shared care relationship between hospital based stroke specialists and community based primary care physicians. Each quarterly intervention includes a pre-visit semi structured telephone interview to assess risk factors and post stroke depression. Based on the pre-visit interview, a report is faxed to the Gp prior to the patient visit. The patient and Gp meet and complete an individualised risk factor

1. Nurse coordinated evidence based quarterly follow up of participants in the community, in a shared care relationship between hospital based stroke specialists and community based primary care physicians. Each quarterly intervention includes a pre-visit semi structured telephone interview to assess risk factors and post stroke depression. Based on the pre-visit interview, a report is faxed to the Gp prior to the patient visit. The patient and Gp meet and complete an individualised risk factor worksheet including relevant diagnostic tests. The completed worksheet is returned to the coordinating hospital to facilitate potential shared care. Therefore, coordinated visits to the patients Gp in the first year following the index stroke. 2. Simultaneously, over the period of 1-year, participants receive risk stratified telemedicine follow-up from the nurse coordinator that includes, education and support. As calculated by a study specific risk calculation algorithm, risk is assigned as high, medium or low. High risk participants are exposed to a greater frequency of telephone follow-up i.e., weekly for 3 months, 3-weekly for 3-months and monthly for 6-months. Low risk participants receive monthly telephone calls. The frequency may be modified according to changes in individual patient needs. Components of telephone calls include a range of established behavioral modification strategies to target health related lifestyle modification, plus health education, carer support, medication compliance and the potential for referral for specialist support.

Sponsors

National Ageing Research Institute (NARI) of Melbourne.
Lead SponsorCharities/Societies/Foundations

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Diagnosis of stroke (ischemic or hemorrhagic) or transient ischemic attack. 2. Returning to the care of the primary care physician upon discharge from acute care or rehabilitation. 3. Is able to provide informed consent. 4. 18 years of age or older

Exclusion criteria

1. Diagnosed with dissection, subarachnoid hemorrhage, traumatic intracerebral hemorrhage or subdural hematoma. 2. Unable to return to the care of their primary care physician. 3. Unable to provide informed consent.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026