A Randomised Placebo-Controlled Trial to compare Dilute Bleach Baths with Water treatment of Children with Eczema.

When Children with Eczema are treated with Dilute Bleach baths and they are compared with Children with Eczema who have Water baths is there a difference in the Eczema as measured by the Eczema Area and Severity Index (EASI)?

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000260921

Enrollment

Registered

2011-03-10

Start date

2011-04-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A trial to compare twice weekly dilute bleach baths with water baths in children with eczema. The hypothesis is that bacterial colonisation may be less after the bleach baths and so the eczema should improve. Bacterial swabs will also be taken at the start and after six weeks of baths to assess bacterial colonisation rates before and after the dilute bleach baths. The amount of bleach used is 1 ml per litre of bath water (giving Sodium hypochlorite 0.004% in the bath water). All participants will also have standard eczema treatments with moisturisers and steroid creams as required.

Interventions

Twice weekly dilute bleach baths for six weeks. Add 1 ml of household bleach per litre of bath water. This results in Sodium hypochlorite 0.004% concentration in the bath water.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

1 Years to 15 Years

Healthy volunteers

Inclusion criteria

Children with Eczema (Atopic Dermatitis)

Exclusion criteria

Previous use of antibiotics in the 6 weeks prior to enrolment in the trial. Previous allergic reaction or severe exacerbation of asthma after contact with bleach. Children who do not have a family doctor to help monitor progress whilst in the trial.

Outcome results