None listed
Conditions
Brief summary
The aim of this study is to determine whether the consumption of lutein with milk increases exercise-self efficacy, leading to increased exercise participation in older adults. The overall purpose is to provide scientific substantiation for a novel nutritional supplement aimed at increasing physical activity to improve health and reduce disability in an ageing population. Preliminary research in rats demonstrated that the consumption of lutein-fortified milk increased the duration of voluntary wheel running. This increased wheel running was associated with enhanced muscle development and reduced body fat. The mechanism by which the lutein-fortified milk stimulated the rats to increase the volume of wheel running is not known, but it seems likely that there was some change in their mood which promoted exercise behaviour. If this supplement were to elicit a similar effect in people being encouraged to undertake regular physical activity this might result in them undertaking a greater volume of exercise and thus potentially achieving health benefits.
Interventions
All participants will be encouraged to undertake regular physical activity involving the performance of at least 150 min/week of moderate to vigorous activity in accordance with the national physical activity guidelines for Australian adults for 3 weeks (Week 1-4). The physical activity will be left up to the participant to perform.
In addition to undertaking regular physical activity, participants will be allocated to the treatment group (capsules containing 21 mg/day of lutein) or the placebo
All participants will be encouraged to undertake regular physical activity involving the performance of at least 150 min/week of moderate to vigorous activity in accordance with the national physical activity guidelines for Australian adults for 3 weeks (Week 1-4). The physical activity will be left up to the participant to perform. In addition to undertaking regular physical activity, participants will be allocated to the treatment group (capsules containing 21 mg/day of lutein) or the placebo group. Participants will be required to consume a capsule and 250 ml of full cream milk at the same time everyday, preferably in the morning, for 4 weeks (Week 0-4).
Sponsors
Meiji Dairies Corporation
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
Aged between 60 and 80 yrs Not currently participating in sufficient physical activity levels to meet Australia guidelines BMI between 18.5 and 29.9 kg/m2
Exclusion criteria
Typically consume more than two standard serves of dairy products per day Non weight-stable (body weight change of >3 kg in last 3 months) Acute or terminal illness Moderate or severe cognitive impairment (inability to understand and provide written informed consent and/or follow instructions) Any medical condition that might be exacerbated by exercise or might limit exercise training Current smoker or only recently quit smoking (smoked any cigarettes within the last 12 months) Alcohol consumption (more than four alcoholic drinks per day) Coeliac disease Lactose intolerance Allergy to cow’s milk protein Diabetes Medications (or supplements) changed significantly during the last 12 weeks Consume carotenoids (lutein, astaxanthin, zeaxanthin) supplements daily Any other condition which in the opinion of the investigators might confound the outcomes of the study
Outcome results
None listed