None listed
Conditions
Brief summary
This study will assess whether new cerals made with a new variant of barley deliver digestive health benefits to consumers.
Interventions
We will be testing 4 different breakfast cereals, a conventional barley cereal, 2 new barley cereals and a refined cereal. Barley cereals are derived from Barley lines that differ in nutrient composition. Participants will consume each of the 4 test foods in 4 week blocks, with each test food period to be separated by 2 weeks. For the duration of the study participants will be required to consume their usual diet with some restrictions to ensure it is low in fibre. For each 4 week test period, t
We will be testing 4 different breakfast cereals, a conventional barley cereal, 2 new barley cereals and a refined cereal. Barley cereals are derived from Barley lines that differ in nutrient composition. Participants will consume each of the 4 test foods in 4 week blocks, with each test food period to be separated by 2 weeks. For the duration of the study participants will be required to consume their usual diet with some restrictions to ensure it is low in fibre. For each 4 week test period, they will be required to consume 50g of the test food daily. At the beginning of the study and at the end of each 4 week testing period participants will be required to attend the Clinic for a 15 minute appointment to discuss digestive health and prior to the visit collect a 48 hour faecal and urine collection and 3 short questionnaires (product consumption checklist, 3-day food diary and physical activity questionnaire). At baseline only, they will be required to undergo a whole body and forearm DEXA scan.
Sponsors
CSIRO Food Futures National Research Flagship
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
Male or female, aged 20-80 years. BMI 19-25. Not received any medication that in the opinion of the investigator could interfere with the study and no medications likely to modulate gut function. No history of alcohol or drug abuse. No participation in a study with any experimental drug within 30 days of commencement of the study. No presence of gastrointestinal, renal, hepatic disease or intestinal inflammation. Willing to comply with study diet and alcohol restrictions.
Exclusion criteria
Use of any form of drug therapy or medication or supplements that may interfere with bowel function (such as antibiotics, laxatives etc). Known or suspected personal history or family history of adverse events, hypersensitivity or intolerance to consumption plant-based foods which will be tested in this study. Person considered by the investigator to be unwilling, unlikely or unable to comprehend or comply with the study protocol and restrictions. Unwilling or unable to collect bowel motions as required.
Outcome results
None listed