Quantifying the effect of the sedative alprazolam on brain electrical activity using the Brain Anaesthesia Response monitor

Quantifying the effect of alprazolam on brain electrical activity in healthy males using the BAR monitor

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000144910

Enrollment

Registered

2011-02-08

Start date

2011-02-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study is designed to evaluate a new method for monitoring the effects of sedatives on the brain's electrical activity. The method involves a sophisticated, physiologically motivated, algorithm for the analysis of the scalp recorded electroencephalogram.

Interventions

Single 1 mg oral alprazolam dose

Study design

Allocation

Non-randomised trial

Primary purpose

Diagnosis

Eligibility

Sex/Gender

Male

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

non-smoker, no history of anxiety, depression or other psychiatric disorder, no history of epilepsy or other neurological disorder known to affect resting EEG

Exclusion criteria

consumption of any pharmaceutical product/medicine in last 30 days, consumption of vitamin complex or herbal extract withion last 30 days, history of alcohol or drug abuse

Outcome results