None listed
Conditions
Brief summary
The purpose of this study was to determine whether the administration of Cyproheptadine (CH) was able to induces weight gain, improving food consumption and pulmonary function in patients with cystic fibrosis (CF).
Interventions
The intervention group will receive cyproheptadine for a period of 12 weeks and the control group will receive placebo for the same period.
In the first week 2mg three times a day
In the next weeks 4mg three times daily
Mode of administration: Syrup with a concentration of 1 ml
The patient gets two bottles:
In the first week, in the intervention group
taking the syrup, where each ml is the concentration of 2 mg of cyproheptadine.
In the rest week, the intervention group takes the syrup ha
The intervention group will receive cyproheptadine for a period of 12 weeks and the control group will receive placebo for the same period. In the first week 2mg three times a day In the next weeks 4mg three times daily Mode of administration: Syrup with a concentration of 1 ml The patient gets two bottles: In the first week, in the intervention group taking the syrup, where each ml is the concentration of 2 mg of cyproheptadine. In the rest week, the intervention group takes the syrup has a concentration of 4 mg per ml.
Sponsors
Regina Nejedlo
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* patients aged between 5 and 18 years; * qualified to spirometry; * weight / age <100%.
Exclusion criteria
Patients with intolerance to antihistamines, patients using sedative or narcotic drugs, patients that have taken appetite stimulants or steroids for 30 days before the study, inability to do spirometry.
Outcome results
None listed