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Characterising the nature, and clinical significance of body and limb movements during adult sleep using multi-site accelerometry

Characterising the nature, and clinical significance of body and limb movements during adult sleep using a continuous multisite accelerometry system (CMAS) versus standard polysomnogram indices in patients undergoing diagnostic polysomnograms

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12611000119998
Acronym
N/A
Enrollment
50
Registered
2011-02-02
Start date
2011-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The general aim of this research is to investigate whether continuous tri-axial accelerometry is a usfull tool for the qunatification, and characterisation of movements during sleep in a clinical diagnosis setting. This research targets: - Movements as a consequence of movement disorders (Such as Periodic Leg Movements During Sleep), - Movements as a consequence of arousals during the night - Movements as a conqequence of respiratory events during the night 50 adults attending The Princel Charles Hospital Sleep Service for a Diagnostic Polysomnogram (sleep study) will be recruited. In addition to the standard physiological channels recorded in a sleep study, Multiple accelerometers will be strategically placed on each subject (ankle and big toe, wrist and middle finger and central thorax). Data will be analysed to determine whether: - The amplitude of movements observed using accelerometry predict cortical arousal - Continuous triaxial accelerometry may be used to automatically classify sleep from wake more accurately than commercial actigraphs - Multisite accelerometry allows primary limb movements to be distinguished from gross body movements as a consequence of arousal or other events - Indices of movement events correlate with qualtiy of life measures

Interventions

A continuous multisite accelerometry system will be applied in addition to conventional polysomnogram channels, for the duration of a overnight polysomnogram (typically 6-9 hours). Each of the 50 participants will be studied for the duration of a single overnight polysomnogram. The duration to complete all 50 studies is anticipated to be approximately 12 months. The continuous multisite accelerometry system consists of 3 separate units, each containing a digital triaxial accelerometer: - O

A continuous multisite accelerometry system will be applied in addition to conventional polysomnogram channels, for the duration of a overnight polysomnogram (typically 6-9 hours). Each of the 50 participants will be studied for the duration of a single overnight polysomnogram. The duration to complete all 50 studies is anticipated to be approximately 12 months. The continuous multisite accelerometry system consists of 3 separate units, each containing a digital triaxial accelerometer: - One located on the patients wrist. This unit also has a lead with an additional accelerometer which will be taped to the participants middle finger - One located on the participants ankle. This unit also has a lead with an additional accelerometer which will be taped to the participants middle finger - One located on the participants chest (just below sternal notch) Each unit continuously measures acceleration, and transmits data via a low power radio link to a logging PC.

Sponsors

The University of Queensland
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

Patients referred to The Prince Charles Hospital Sleep Service for an overnight diagnostic polysomnogram for any reason

Exclusion criteria

- Women who are pregnant - People who are highly dependant on medical care - Perople with degenerative neuromuscular disorders such as Parkinson's hisease and Huntington's chorea where a resting involuntary tremor is present -People, who as observed on the PSG, have an uninterpretable EEG

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026