None listed
Conditions
Brief summary
The purpose of this research is to examine how different fish oil (omega-3 fatty acids) concentrates can influence platelet activity and improve platelet function in males and females. There is evidence in the published literature that response to fish oil supplementation is influenced by a gender-specific manner. Moreover, fish oil supplements contain different concentration ratios of the active ingredients, EPA and DHA. This research project will determine how gender influences fish oil supplementation so that males and females can receive maximum benefit against cardiovascular disease risk.
Interventions
The study design is a double-blinded placebo controlled trial.
There are 3 groups of participants of equal gender randomised to a treatment group to receive either fish oil capsules or placebo. The 3 treatment groups in this trial are:
(i) 2 x 1g dose 500mg Docosahexaenoic Acid (DHA) [1:5 EPA/DHA]
OR
(ii) 2 x 1g dose 500mg Eicosapentaenoic Acid (EPA) [5:1 EPA/DHA]
OR
(iii) 2 x 1g dose Placebo (sunola oil)
Participants are required to consume the above dose, corresponding to the group they h
The study design is a double-blinded placebo controlled trial. There are 3 groups of participants of equal gender randomised to a treatment group to receive either fish oil capsules or placebo. The 3 treatment groups in this trial are: (i) 2 x 1g dose 500mg Docosahexaenoic Acid (DHA) [1:5 EPA/DHA] OR (ii) 2 x 1g dose 500mg Eicosapentaenoic Acid (EPA) [5:1 EPA/DHA] OR (iii) 2 x 1g dose Placebo (sunola oil) Participants are required to consume the above dose, corresponding to the group they have been randomised to, daily for a 4 week dietary intervention period. Participants are assessed at baseline and after the 4 week period.
Sponsors
University of Newcastle
Study design
Allocation
Randomised controlled trial
Primary purpose
Prevention
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy participants aged 18 years or above.
Exclusion criteria
Participants diagnosed with any hematological or cardiovascular disorders and are taking fish oil capsules or medication affecting coagulation.
Outcome results
None listed