None listed
Conditions
Brief summary
Each year CSIRO Food and Nutritional Sciences perform a number of research projects involving human participants. The present study will be investigating genetic differences in taste perception and how they are associated with genetic factors, susceptibility to chronic disease and dietary intake.
Interventions
During this study participants will be involved in an exploratory discovery study, during which their dietary intake, weight status and taste sensitivity will be evaluated and compared with 1) allelic variation in taste receptor genes and 2) relative expression of taste receptor genes upon the tongue. A total of five testing sessions will be required for this study, including four x 60 minute taste tests, and one 90 minute session during which tongue tissue will be collected, taste papillae coun
During this study participants will be involved in an exploratory discovery study, during which their dietary intake, weight status and taste sensitivity will be evaluated and compared with 1) allelic variation in taste receptor genes and 2) relative expression of taste receptor genes upon the tongue. A total of five testing sessions will be required for this study, including four x 60 minute taste tests, and one 90 minute session during which tongue tissue will be collected, taste papillae counted, and the questionnaires (food frequency questionnaire and implict attitudes test) will be completed. Taste testing will be done to determine detection thresholds for each tastant, as well as difference thresholds for each tastant. The detection threshold is the lowest concentration of a tastant required for it to be detected within the mouth, wheras the difference threshold is the concentration of a tastant required for it to be perceived as different from an identical tastant, at a different concentration. Testing will take place over a one month period, and all testing will be seperated by at least 24 hours.
Sponsors
Dr Conor Delahunty
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
For these studies, we are specifically seeking individuals who are: - 18 years or older - Living in metropolitan Sydney - Proficient in both written and spoken English - Able to attend testing sessions between the hours of 9:00 am - 5:00pm Monday to Friday
Exclusion criteria
For these studies we are specifically excluding individuals based upon the following criteria: - Adults with known medical conditions known to affect weight (hyperthyroidism, Cushing syndrome etc) - Individuals who are currently on, or have been on a diet, or specific dietary routine within the past 3 months - Individuals who have experienced fluctuations in their weight by > 3 kg in the past 3 months - Individuals who do not have adequate taste function - Individuals who are restrained eaters (as defined by a score of > 12 on factor one of the eating attitudes test - Individuals who are allergic to, or do not wish to consume dairy products - Individuals over the age of 55 years -Smokers
Outcome results
None listed