Effect of endotracheal tube on ventilator associated pneumonia in Intensive Care Unit patients

Effect of EVAC endotracheal tube on decreasing ventilator associated pneumonia in critically ill patients admitted to Intensive Care Units

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000038998

Enrollment

Registered

2011-01-12

Start date

2011-02-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Almost 10-28% of patients admitted to intensive Care Units(ICU) suffered from Ventilator Associated Pneumonia(VAP) which leads to increasing mortality,ICU length of stay and mortality. As micro or macroaspiration of subglottic secretions is one of the most important risk factors for developing VAP, adevice that can suction these secretion may help to decreasing VAP. So in this study we want to evaluate the efficacy of EVAC endotracheal tube in decreasing VAP in critical ill patients. ninty patients will be enrolled in this study. patient will be allocated to two 45 patient groups. One group will be intubated with EVAC endotracheal tube and the other group will be intubated with standard tube. the Vap rate, mortality, ICU length of stay and duration of mechanical ventilation will be noted for each patient.

Interventions

Intubation of patients with EVAC oral endotracheal tube.(A specific tube with a distal lumen for suctioning of subglottic secretions and very thin cuff with poly urethane material which has not any folds on it after cuff filling). Patients will be intubated minimum 3 days until they will meet extubation criteria.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

Adult patients(more than 18 years old) who will be ventilated for more than 3 days

Exclusion criteria

previous history of mechanical ventilation,pregnancy, Human Immunodefficiency Virus infection, malignancy,Immunosuppressive therapy, leukocyte count less than 1000/mm3

Outcome results