Stem cells for peripheral vascular disease

Double blind, randomised safety and feasibility evaluation of intra-arterial CD34+ cell delivery for severe peripheral arterial disease

Status

Withdrawn

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12611000011987

Enrollment

Registered

2011-01-06

Start date

2011-01-01

Completion date

Unknown

Last updated

2026-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study seeks to establish whether stem cells can be used to treat patients with poor circlation in their legs.

Interventions

A single dose CD34 cells (at a dose of 3 × 10^5 CD34+ cells per kilogram of recipient's body weight), delivered by intra-arterial infusion, delivered in 20 mls saline over 20 minutes

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

Inoperable peripheral arterial disease (PAD) with rest pain or non healing ulcer

Exclusion criteria

Recent acute coronary disease, severe other life threatening illness

Outcome results