None listed
Conditions
Brief summary
This study formally investigates specific breathing exercises, using a threshold device, for patients who require a breathing machine. It is hoped that the study will demonstrate that this training reduces breathing muscle weakness and also enhances quality of life, with significant improvements even 2 weeks following weaning from the breathing machine. The results of this study will guide physiotherapists in the optimal treatment of breathing muscle weakness for patients who have needed a breathing machine.
Interventions
Inspiratory muscle training using a threshold resistive muscle trainer, performing 5 sets of 6 breaths at an intensity of RPE 5-6 on weekdays. Patients studied while ventilator-dependent will continue to train until weaned. Patients studied post ventilatory weaning will train for 2 weeks on weekdays only. All IMT sessions will be supervised by a physiotherapist.
Sponsors
Bernie Bissett
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
All patients admitted to ICU who: - are mechanically ventilated for 7days or longer - are aged 16 years or older - are alert and able to co-operate with training - are able to provide informed consent
Exclusion criteria
Patients will be excluded from the study if they are: - age < 16 years - unwilling to consent - previously included in the study - pregnant - mechanically ventilated less than 7days - not alert or able to co-operate with training - not able to provide informed consent - requiring high levels of ventilatory support (eg PEEP > 15 cmH20, FiO2 > 0.60) where the treating team (medical and / or physiotherapy) deems risks of brief disconnection from ventilation unacceptable
Outcome results
None listed