Can olive leaf extract reduce the risk of metabolic disease?

Can olive leaf extract improve insulin sensitivity in middle aged males? A randomized cross-over trial of olive leaf extract in males aged 35 -55, with a body mass index of 25 - 30.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610001082099

Enrollment

Registered

2010-12-08

Start date

2011-04-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of the study is to formally assess the impact of olive leaf extract on insulin sensitivity. It will be given as a supplement, without altering other aspects of diet or lifestyle.

Interventions

Olive leaf extract (Oleuropein) 66mg (15mL), oral once daily for 12 weeks. Crossed over to placebo with a 6 week washout between interventions. There will be no lead in period.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

Male

Age

35 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

Males aged 35 to 55. BMI 25 - 30

Exclusion criteria

Any medications BMI outside inclusion range Smokers Diabetes Cardiovascular disease.

Outcome results