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The effect of glycaemic load on satiety

The effect of a low glycaemic load diet and a high glycaemic load diet, matched for macronutrient level and type of fibre, on glucose and satiety over a 12 hour period in healthy adult males.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610001060033
Enrollment
24
Registered
2010-12-02
Start date
2010-07-05
Completion date
2010-07-16
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Satiety measures levels of hunger and feelings of fullness after a meal and stops us eating more. There are many physiological and psychological processes involved and our apparent inability to control our food intake is thought to be contributing to the rising levels of obesity and its associated health problems. In this study we aim to examine some of the factors involved in satiety by measuring an individual’s response to food over a period of twelve hours. Food will be high glycaemic load or low glycaemic load which is a way of measuring the type of carbohydrate (CHO) in food and how quickly we can digest it to release glucose into the blood. The slower the digestion of CHO, the more satiating the food. Subjects will be given breakfast, morning tea, lunch, afternoon tea and dinner. Blood glucose measurements will be taken throughout the day and subjects will also be asked to rate feelings of hunger, fullness and how much more food they could eat. Participants will also be asked to rate if they feel stressed or anxious and also asked to complete some easy tasks to measure how well they remember and recall information.

Interventions

Diet varying in glycaemic load (one high (GL= 206), one low (GL=126) fed over 12 hour period. Diets consisted of everyday food items. The high GL diet included white bread, jam, lucozade, pizza, macaroni cheese whilst the low GL diet consised of soy and linseed bread, milo, cheese, hummus, salad, falafel, yoghurt, fruit). Meals will be given at 08.00 (breakfast), 10.00 (morning tea), 13.00 (lunch), 15.00 (afternoon tea) and 18.00 (dinner). Measurements of blood glucose levels; satiety (vis

Diet varying in glycaemic load (one high (GL= 206), one low (GL=126) fed over 12 hour period. Diets consisted of everyday food items. The high GL diet included white bread, jam, lucozade, pizza, macaroni cheese whilst the low GL diet consised of soy and linseed bread, milo, cheese, hummus, salad, falafel, yoghurt, fruit). Meals will be given at 08.00 (breakfast), 10.00 (morning tea), 13.00 (lunch), 15.00 (afternoon tea) and 18.00 (dinner). Measurements of blood glucose levels; satiety (visual analogue scales);mood (state trait anxiety scales); cognitive function (mini mental state exam) were made through the course of the day. As this is a cross over study, participants will have a period of at least 7 days between each visit.

Sponsors

Lifestyle Foods
Lead SponsorOther Collaborative groups

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
Male
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

Subjects will be healthy male individuals (age 18-45) with healthy weight (Body mass index , BMI, 19-25 kg/m2) and normal glucose tolerance (fasting glucose < 5.6 mmol/L). Exclusion criteria will include: smoking, medication, food allergy/intolerance, dieting, physical or mental illness

Exclusion criteria

Exclusion criteria include: smoking, medication, food allergy/intolerance, dieting, physical or mental illness

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026