None listed
Conditions
Brief summary
Prolonged elevation of fat (triglyceride) concentrations in the blood after a meal increases the risk of developing cardiovascular disease. Moderate to vigorous physical activity is highly effective at lowering the concentration of fat in the blood after a meal. However, studies in rats suggest that frequent sessions of low level activity performed throughout the day may be just as effective as a single session of more intense exercise at lowering the concentration of fat in the blood after a meal. The aim of this study is to compare the effects of one session of 30 minutes of moderate intensity physical activity, to the effects of performing one minute and 40 seconds of low-level physical activity every 30 minutes throughout the day on concentrations of triglyceride, glucose and insulin
Interventions
This is a randomized cross over study, in which, participants will complete the following three, 9 h trials, each separated by at least 7 days: 1) Physical Activity (PA) trial: participants will walk on the treadmill at 60 % of maximal oxygen consumption (VO2max) for 30 min prior to consuming the first meal replacement beverage (MRB) then remained seated for the remainder of the trial; 2) Active Living (AL) trial: participants will walk on the treadmill at the same speed and incline as PA, for 1 min and 40 s every 30 min throughout the trial; and 3) Sedentary (SE) trial: participants will remain seated for the duration. In each trial participants will be fed three MRBs, each providing 0.46 g fat, 0.54 g protein and 1.12 g carbohydrate per kg at 60, 240 and 420 min.
Sponsors
Study design
Eligibility
Inclusion criteria
Healthy men and women who do not regularly undertake more than 3 hours of physical activity a week.
Exclusion criteria
Previously diagnosed cardiovascular disease, diabetes, metabolic disease, high cholesterol or high blood pressure Resting blood pressure greater than 140/90 History of venous thrombosis or any abnormality of blood clotting Smoking Medication known to influence lipid or carbohydrate metabolism