The Role of male sex hormone in Angiogenesis and Endothelial Progenitor Cell Mobilisation

The Role of Androgens in Angiogenesis and Endothelial Progenitor Cell Mobilisation

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000952044

Enrollment

Registered

2010-11-05

Start date

2010-01-15

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to assess the effects of testosterone on endothelial progenitor cells numbers and function in men. By understanding the effects of testosterone on endothelial progenitor cells, we may be able to better understand the potential role that male sex hormones may play in maintaining heart and blood vessel function in men. This research may ultimately lead to new treatments to help with heart and blood vessel repair. To Public: This study aims to assess the effect of male sex hormone on the male stem cells. By understanding the effect we may be able to use male sex hormone to maintain human heart and blood vessel function in men.

Interventions

Primoteston (testosterone enanthate) 250mg intramuscular injection weekly for 6 weeks

Study design

Allocation

Randomised controlled trial

Primary purpose

Prevention

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

all males, except for those aged 35-55 years old, and 18 is the minimum age

Exclusion criteria

diabetes, prostate problem, on statin treatment, significant medical illness

Outcome results