A study to assess the efficacy of a probiotic in the restoration of bowel function of patients undergoing reversal of ileostomy.

A study to assess the efficacy of VSL#3 in the restoration of bowel function of patients undergoing reversal of ileostomy.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000932066

Enrollment

Registered

2010-11-03

Start date

2005-03-02

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients experience a period of altered bowel function after the reversal of a temporary loop ileostomy. This study aimed to assess whether a probiotic preparation, VSL#3, improved bowel function during the first month after loop ileostomy reversal.

Interventions

VSL#3 Dosage: 2.5g sachet twice daily for 4 weeks Ingredients: 450 billion lactic acid bacteria, cornstarch Mode: orally mixed with water or apple juice

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Over 18 years of age 2. Able to fill in questionnaires and diary 3. Had an anterior resection or Hartmann's procedure 4. Undergoing reversal of ileostomy

Exclusion criteria

Patients with Coeliac Disease

Outcome results