A proprietary blend of Phellodendron and Crape Myrtle improves glucose tolerance in response to an oral dextrose load in exercise-trained non-diabetic men

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000928011

Enrollment

Registered

2010-11-02

Start date

2010-07-15

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Recently, a finished product containing a proprietary blend of Phellodendron and Crape Myrtle has been developed. It is believed that this product may aid in the management of blood glucose and allow for increased glucose clearance following an oral glucose tolerance test (OGTT). Such effects may be associated with a reduction in adverse outcomes associated with poor blood glucose management, as well as enhanced glucose uptake into skeletal muscle (to be stored as glycogen—an objective of many athletes). In relation to the latter effect, this particular product is purported to act as a nutrient partitioning agent, working to theoretically improve body composition by preferentially shuttling glucose into skeletal muscle as opposed to adipose tissue. The present study sought to investigate the acute effects of this nutritional supplement on serum glucose and insulin in response to an OGTT.

Interventions

1) Oral capsule was the mode of administration a)proprietary blend of 750mg of Phellodendron [bark] and Crape Myrtle [Lagerstroemia Speciosia] stem [Anabolic Pump (TM); USPlabs, LLC, Dallas, TX] b)single dose only 7 day washout period

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

Male

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

Ten healthy, exercise-trained men.

Exclusion criteria

Subjects were not smokers, and did not have diagnosed cardiovascular or metabolic disease (including diabetes). Subjects were not using dietary supplements believed to influence blood glucose disposal.

Outcome results