A randomised controlled trial of 'arthritis relief plus' for osteoarthritis of the knee

A randomised placebo controlled trial of 4jointz for the symptoms of osteoarthritis of the knee

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000877088

Enrollment

140

Registered

2010-10-19

Start date

2010-09-09

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to determine the efficacy of arthritis relief plus for knee osteoarthritis pain. THis is a mix of 20 natural therapies. The design is randomised and double blind for 3 months followed by a one month wash out in 140 patients with significant knee pain due to arthritis.

Interventions

4JOINTZ is a novel combination of synergistic blend of standardised botanical extracts. It is topically applied and massaged directly into the joint(s). Approximately 3 grams or less than half a teaspoon is massaged into the knee joint 3 times a day for a period of 12 weeks.

Study design

Allocation

Randomised controlled trial

Primary purpose

Treatment

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

American Collegeof Rheumatology (ACR) criteria for knee osteoarthritis* - Knee pain and at least 3 of 6 - Age > 50 years - Stiffness < 30 minutes - Crepitus - Bony Tenderness - Bony enlargement - No palpable warmth Pain visual analogue scale >40mm Age >50

Exclusion criteria

- Other forms of arthritis - Xray showing Osteoarthritis Research Society International (OARSI) grade 3 joint space narrowing (JSN) - Significant knee injury within last 6 months - Inability to sign provide informed consent

Outcome results